明尼苏达州大学医学院科学家称：青少年时期被检出胰岛素抵抗可能是成年后患心脏病和糖尿病的预兆。研究员想要比较体重指数和胰岛素抵抗对将来风险的可预测性。
体重指数是当前医生度量超重和肥胖的主要指标。如果一个人的体重指数超过30，无论男性还是女性均判为肥胖。
你可以参阅发表在Hypertension杂志8月22日这一期上的研究报告。
研究小组组长Alan R. Sinaik博士说：“我们发现胰岛素抵抗独立于体重指数，是一个增加心脏病危险的独立因素。目前每个人都有肥胖趋势。如果能在儿童期和青春期避免体重增加，这对青年时期的（患病）风险将有积极的影响。自从发现胰岛素抵抗是一种独立于体重指数的重要危险因素后，应该将注意力转到探索预防胰岛素抵抗的策略上来。”
研究员说，采用合理的饮食以及增加运动锻炼是预防胰岛素抵抗最好的方法。
357名被观察的学龄儿童接受了全面的医学检查，当他们13岁时，接受了全面的医学检查，包括胰岛素敏感性。细胞摄入葡萄糖的能力越差，胰岛素抵抗的程度就越严重。在他们15和19岁时分别再次接受了该项检查。
研究员发现13岁时有胰岛素抵抗的人，在19岁时患高血压和血脂升高的可能性会大大增加。因此13岁时发现胰岛素抵抗是今后患心脏病和糖尿病的良好指征。高血脂和高血压将会明显增加中风和患某些心脏病的风险。
Teenage Insulin Resistance May Be Predictor Of Heart Disease Later On
Main Category: Pediatrics News
Article Date: 21 Aug 2006 - 15:00pm (PDT)
If insulin resistance is detected in a teenager, this could be a predictor of heart disease and diabetes later on during adulthood, say scientists from the University of Minnesota Medical School. The researchers wanted to compare the predictability of BMI (body mass index) and insulin resistance on future risk factors.
BMI is the main way doctors today measure for overweight and/or obesity. If a person's BMI is over 30 he/she is obese.
You can read about this study in the journal Hypertension, August 22 issue.
Team leader,Dr. Alan R. Sinaiko, said "We found that insulin resistance itself, independent of body-mass index, was an indicator of increased risk. Everyone today is tuned into fatness. If you can keep people from gaining weight in childhood and adolescence, it will have a positive impact on risk as a young adult. Since insulin resistance is important independent of body-mass index, this suggests attention should be paid to trying to develop strategies against it."
The researchers say that adopting good diet and becoming more physically active are the best ways of tackling looming insulin resistance.
357 schoolchildren were monitored. They received a complete medical check up, including how effective their insulin management was, when they were 13. The lower the uptake of glucose into cells the higher the insulin resistance. Insulin management tests were carried out again on the same children when the children were 15 and then 19.
The researchers found that those with insulin resistance when they were 13 were much more likely to experience hypertension (high blood pressure) and elevated levels of lipids in their blood (triglycerides) when they reached 19. Therefore insulin resistance at 13 could be a good predictor of heart disease and diabetes later in life. High blood triglyceride levels and hypertension significantly raise a person's risk of having a stroke or some kind of heart disease.
Influence of Insulin Resistance and Body Mass Index at Age 13 on Systolic Blood Pressure, Triglycerides, and High-Density Lipoprotein Cholesterol at Age 19Alan R. Sinaiko; Julia Steinberger; Antoinette Moran; Ching-Ping Hong; Ronald J. Prineas; and David R. Jacobs Jr
Hypertension 2006, doi:10.1161/01.HYP.0000237863.24000.50
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